ZLN005 hydrochloride - CAS 2319647-97-5

ZLN005 (hydrochloride) is an activator of the peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α) . It enhances the expression of PGC-1α and downstream genes in skeletal muscle cells, leading to improved glucose utilization and fatty acid oxidation. In diabetic db/db mice, ZLN005 (hydrochloride) elevates the transcription of PGC-1α and downstream genes in skeletal muscle, boosts fat oxidation, and enhances glucose tolerance, pyruvate tolerance, and insulin sensitivity.

Metabolism

2319545

C17H19ClN2

286.8

Cl.N=1C=2C=CC=CC2NC1C=3C=CC(=CC3)C(C)(C)C

-20°C

Ice Packs

Small Compound