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Molfinity

ZM-447439 - CAS 331771-20-1

ZM-447439 - CAS 331771-20-1

MF-0052799-01

$43.64 USD
$43.64 USD
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Product Details

  • Bioactivity

    ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.

  • Target

    Src, Apoptosis, Aurora Kinase, MEK

  • Related Pathways

    Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, MAPK, Angiogenesis, Cell Cycle/Checkpoint, Apoptosis

  • CAS Number

    331750

  • Purity

    0.9959

  • Molecular Formula

    C29H31N5O4

  • Molecular Weight

    513.59

  • SMILES

    COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCCN1CCOCC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound