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ZN-A-1041 - CAS 2414056-31-6
ZN-A-1041 - CAS 2414056-31-6
SKU:MF-0121571-01
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Product Details
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Bioactivity
ZN-A-1041 is an inhibitor of HER2 in BT474 cells with an IC50 of 9.5 nM and wt-EGFR in H838 cells with an IC50 of 12 μM. It can be utilized for cancer and inflammation research [1].
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Target
EGFR
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Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis
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CAS Number
2414056-31-6
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Molecular Formula
C27H26F2N8O3
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Molecular Weight
548.54
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SMILES
O(C=1C=2C(NC3=CC(C)=C(OC4=CC=5N(C=N4)N=CN5)C=C3)=NC=NC2C=CC1OC)[C@H]6C(F)(F)CN(C)CC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound