Zolunicant - CAS 188125-42-0

Zolunicant (MM-110) is a potent nicotinic α3β4 receptor inhibitor with an IC50 of 0.90 μM, showing promise in combating addiction. It effectively reduces self-administration of addictive agents such as morphine, cocaine, methamphetamine, nicotine, and ethanol in rat models, indicating its potential as a treatment for various forms of drug abuse [1]. Additionally, Zolunicant exhibits strong leishmanicidal activity against Leishmania amazonensis, expanding its therapeutic prospects [2].

Parasite, AChR

Microbiology/Virology, Neuroscience

188083

C22H28N2O3

368.47

C(OC)(=O)[C@]12[C@]3([N@](CC(C1)(C[C@@H]3CCOC)[H])CCC4=C2NC=5C4=CC=CC5)[H]

-20°C

Ice Packs

Small Compound