Zonisamide - CAS 68291-97-4

Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels results in a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may lower the uptake of the inhibitory neurotransmitter GABA while increasing the uptake of the excitatory neurotransmitter glutamate.

Sodium Channel, Calcium Channel, Apoptosis, Carbonic Anhydrase

Apoptosis, Metabolism, Membrane transporter/Ion channel

68190

>99.99%

C8H8N2O3S

212.23

C(S(N)(=O)=O)C=1C=2C(ON1)=CC=CC2

-20°C

Ice Packs

Small Compound