ZW-1226 - CAS 2351940-23-1

ZW-1226 is a selective MRP1 inhibitor that reduces the uptake activity of MRP1 vesicles by 65% at a concentration of 5 μM. It inhibits MRP1 in a GSH-dependent manner and exhibits considerable selectivity towards MRP1 over other primary ABC transport proteins (including P-gp, BCRP, MRP2, and MRP3) .

2351940-23-1

C25H16N4O3

420.42

N#CC=1C=CC=2C=C3C(=O)NC(=O)N=C3N(C4=CC=C(OCC=5C=CC=CC5)C=C4)C2C1

-20°C

Ice Packs

Small Compound