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Molfinity
ZX-29 - CAS 2254805-62-2
ZX-29 - CAS 2254805-62-2
SKU:MF-0018986-01
Regular price
$100.56 USD
Regular price
Sale price
$100.56 USD
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Product Details
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Bioactivity
ZX-29 is a potent and selective inhibitor of ALK with IC50 values of 2.1 nM, 1.3 nM, and 3.9 nM for ALK, ALK [L1196M], and ALK [G1202R] mutations, respectively. It also induces protective autophagy and exhibits antitumor effects.
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Target
ALK, Autophagy, Apoptosis
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Related Pathways
Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis
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CAS Number
2254741
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Purity
0.9951
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Molecular Formula
C23H28ClN7O3S
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Molecular Weight
518.03
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SMILES
COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound